COVID-19 Evidence Reviews
as of 7/10/20
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Updated Reviews
 
= living review
= draft/preprint   |  
= meets mimimum quality standards   |  

A review with this mark was peer-reviewed, described systematic search and study selection, and included critical appraisal of primary studies.
latest update
report
7/8/20
A comparison of mortality-
Lvliang L, Zhong W, Bian Z, et al. | J Infect
Aim: To compare mortality risk factors of COVID-19, Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) to provide new strategies for COVID-19 prevention and treatment.
7/8/20
Systematic Review With Met
Kulkarni A, Kumar P, Tevethia HV, et al. | Aliment Pharmacol Ther
Aim: To assess the prevalence of CLD, the incidence of elevated liver chemistries and the outcomes of patients with and without underlying CLD/elevated liver chemistries in COVID-19.
RECENTLY UPDATED
7/8/20
The impact of ethnicity on
Pan D, Sze S, Minhas J, et al. | EClinicalMedicine
Aim: To assess whether ethnicity has been reported in patients with COVID-19 and its relation to clinical outcomes.
RECENTLY UPDATED
7/6/20
Coronavirus Disease (COVID
Kumar-M P, Mishra S, Jha DK, et al. | Hepatol Int
Aim: To systematically study the occurrence of liver injury in COVID-19 and also determine the frequency of liver involvement in COVID-19.
RECENTLY UPDATED
7/3/20
Diagnostic Accuracy of Ser
Bastos M, Tavaziva G, Abidi SK, et al. | BMJ
Aim: To determine the diagnostic accuracy of serological tests for coronavirus disease-2019 (covid-19).
RECENTLY UPDATED
7/3/20
Environmental Weather Cond
Spencer EA, Brassey J, Jefferson T, et al. | Oxford COVID-19 Evidence Service Team
Aim: To explore if climate conditions may influence the spread of SARS-CoV-2.
RECENTLY UPDATED
6/30/20
Outcomes From Intensive Ca
Armstrong RA, Kane AD, Cook TM | Anaesthesia
Aim: To assess the reported ICU mortality for patients with confirmed COVID?19.
RECENTLY UPDATED
CLINICAL CHARACTERISTICS
6/26/20
RAPID RESPONSE: Corticoste
Helfand M | VA Evidence Synthesis Program
Aim: To review the evidence for using corticosteroids to treat acute respiratory distress syndrome in patients with COVID-19.
UPDATED
VA ESP
6/26/20
RAPID RESPONSE: COVID-19:
Duan-Porter W | VA Evidence Synthesis Program
Aim: To explore the length of stay in the intensive care unit (ICU) and time on invasive mechanical ventilation for adult patients with COVID-19.
UPDATED
VA ESP
6/25/20
Clinical features, Diagnos
Tahvildari A, Arbabi M, Farsi Y, et al. | Front Med
Aim: To characterize the clinical, diagnostic, and treatment characteristics of patients presenting with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
6/25/20
What is the evidence to su
Qureshi Z, Jones N, et al. | Oxford COVID-19 Evidence Service Team
Aim: To identify the evidence behind the 2-metre social distancing rule in the context of the still used large vs. small (droplet vs airborne) droplet size dichotomy in route of transmission.
UPDATED
6/24/20
Masks for Prevention of CO
Chou R, Dana T, Jungbauer R, et al. | Ann Intern Med
Aim: To examine the effectiveness of N95, surgical, and cloth masks in community and health care settings for preventing respiratory virus infections, and effects of reuse or extended use of N95 masks.
UPDATED
6/23/20
Application of Telemedicin
Gao Y, Liu R, Zhou Q, et al. | Ann Transl Med
Aim: To assess the effectiveness of telemedicine in reducing transmission of COVID-19 and reducing pressure on medical institutions.
UPDATED
6/23/20
Breastfeeding of Infants B
Yang N, Che S, Zhang J, et al. | Ann Transl Med
Aim: To conduct a rapid review of mother-to-child transmission of COVID-19 during breastfeeding.
UPDATED
6/23/20
Chest Computed Tomography
Lv M, Wang M, Yang N, et al. | Ann Transl Med
Aim: To understand the role of CT for the diagnosis and the main imaging manifestations of patients with COVID-19.
UPDATED
DIAGNOSTICS
6/23/20
Clinical Characteristics o
Wang Z, Zhou Q, Wang C, et al. | Ann Transl Med
Aim: To review the clinical characteristics of children with COVID-19.
UPDATED
CLINICAL CHARACTERISTICS
6/23/20
Effectiveness and Safety o
Lu S, Zhou Q, Huang L, et al. | Ann Transl Med
Aim: To review the evidence on the use of glucocorticoids in treating COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
6/23/20
Effectiveness of Intraveno
Zhang J, Yang Y, Yang N, et al. | Ann Transl Med
Aim: To explore the clinical effectiveness and safety of IVIG in the treatment of children with severe COVID-19.
UPDATED
CANDIDATE THERAPEUTICS
6/23/20
Efficacy and Safety of Ant
Wang J, Tang Y, Ma Y, et al. | Ann Transl Med
Aim: To evaluate the efficacy and safety of antibiotic agents in children with COVID-19, as well as to introduce the present situation of antibiotics use and bacterial coinfections in COVID-19 patients. 
UPDATED
CANDIDATE THERAPEUTICS
6/23/20
Nosocomial Infections Amon
Zhou Q, Gao Y, Wang X, et al. | Ann Transl Med
Aim: To understand nosocomial infection in patients with COVID-19, SARS, and MERS.
UPDATED
6/23/20
Potential Effectiveness an
Shi Q, Zhou Q, Wang X, et al. | Ann Transl Med
Aim: To assess the potential effectiveness and safety of antiviral agents for COVID-19 in children. 
UPDATED
CANDIDATE THERAPEUTICS
6/21/20
Neurological Involvement o
Ghannam MG, Alshaer QA, Al-Chalabi MAC, et al. | J Neurol
Aim: To clarify the neurological complications of SARS-CoV-2 infection including the potential mechanisms and therapeutic options.
UPDATED
6/20/20
Antithrombotic therapies i
Maldonado E, Tao D, Mackey K | J Gen Intern Med
Aim: To synthesize evidence on thromboembolism incidence and outcomes with antithrombotic therapies in COVID-19.
UPDATED
VA ESP
CANDIDATE THERAPEUTICS
6/20/20
Asthma and COVID-19 in chi
Castro-Rodriguez JA, Forno E | Pediatr Pulmonol
Aim: To review the evidence on the role of asthma in children with COVID-19 and the risk of infection.
UPDATED
6/19/20
Efficacy of cloth face mas
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the efficacy of cloth face masks in helping to prevent the spread of COVID-19.
UPDATED
6/18/20
International Public Healt
Tabari P, Amini M, Moghadami M, et al. | Iran J Med Sci
Aim: To determine countries’ public responses to the epidemic of COVID-19 and how they developed administrative approaches towards the outbreak.
UPDATED
6/18/20
Telehealth in Urology: A S
Novara G, Checcucci E, Crestani A, et al. | Eur Urol
Aim: To perform a systematic review of the literature and evaluate all the available studies on urological applications of telehealth.
6/17/20
A Systematic Review and Me
Grover A, Oberoi M | Eur Heart J Cardiovasc Pharmacother
Aim: To review the evidence on the continued use of angiotensin converting enzyme inhibitors (ACEI) and angtiotensin receptor blockers (ARBs) in patients with COVID-19.
UPDATED
6/17/20
High-flow nasal cannula fo
Agarwal A, Basmaji J, Muttalib F, et al. | Can J Anaesth
Aim: To describe the efficacy and safety of HFNC in acute hypoxemic respiratory failure; and to determine the risk of dispersion, aerosol generation and associated transmission of COVID-19 with HFNC.
UPDATED
WHO COLLABORATIVE
6/14/20
MERS-CoV and SARS-CoV Infe
Bonilla-Aldana DK, Cardona-Trujillo MC, García-Barco A, et al. | Infez Med
Aim: To review the evidence on the role of animals as potential reservoirs for MERS-CoV and SARS-CoV.
UPDATED
6/12/20
Does coronavirus affect th
Almufarrij I, Uus K, Munro KJ | Int J Audiol
Aim: To investigate audio-vestibular symptoms associated with coronavirus.
UPDATED
CLINICAL CHARACTERISTICS
6/12/20
Systematic review of inter
Chiesa-Estomba CM, Lechien JR, Calvo-Henriquez C, et al. | Oral Oncol
Aim: To summarize in a systematic way the available recommendations from 18 guidelines from all over the world.
UPDATED
6/9/20
Rates of Maternal and Peri
Huntley BJF, Huntley ES, Di Mascio D, et al. | Obstet Gynecol
Aim: To ascertain the frequency of maternal and neonatal complications, as well as maternal disease severity, in pregnancies affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
UPDATED
6/8/20
Risk factors for mortality
Parohan M, Yaghoubi S, Seraj A, et al. | Aging Male
Aim: To summarize available findings on the association between age, gender, comorbidities and risk of death from COVID-19 infection.
UPDATED
6/7/20
Cardiovascular complicatio
Kunutsor S, Laukkanen | J Infect
Aim: To review the evidence on cardiovascular complications associated with COVID-19.
UPDATED
6/5/20
Comparison of Confirmed CO
Pormohammad A, Ghorbani S, Baradaran B, et al. | Rev Med Virol
Aim: To review the evidence on clinical and laboratory characteristics of COVID-19 infected patients.
UPDATED
CLINICAL CHARACTERISTICS
6/5/20
Workforce reconfiguration
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence regarding temporary workforce reconfigurations such as splitting of teams and establishing social distancing protocols within teams to minimise staff exposure to COVID-19.
UPDATED
6/4/20
The role and response of p
Mitchell S, Maynard V, Lyons V, et al | Oxford COVID-19 Evidence Service Team
Aim: To review the evidence on the role and reponse of primary care and community nursing services in the delivery of palliative care in epidemics and pandemics.
6/3/20
Systematic review and crit
Wynants L, Van Calster B, Bonten MMJ | BMJ
Aim: To review and critically appraise published and preprint reports of models that aim to predict either (i) presence of existing COVID-19 infection, or (ii) future complications in individuals already diagnosed with COVID-19
UPDATED
6/3/20
The need of health policy
Iannone P, Castellini G, Coclite D, et al. | PLoS One
Aim: To assess the efficacy of N95 respirators versus surgical masks for the prevention of respiratory tract infections transmission among HCWs.
UPDATED
6/2/20
Mast cell stabilisers, leu
Raymond M, Ching-A-Sue G, Van Hecke O | Oxford COVID-19 Evidence Service Team
Aim: To review the evidence on mast cell stabilizers, leukotriene antagonists, and antihistimines in COVID-19.
UPDATED
6/1/20
Markers of liver injury an
Kunutsor S, Laukkanen J | J Infect
Aim: To review the evidence on clinical characteristics and outcomes of liver injury in COVID-19 patients.
UPDATED
CLINICAL CHARACTERISTICS
6/1/20
Physical distancing, face
Chu DK, Akl EA, Duda S, et al. | Lancet
Aim: To investigate the effects of physical distance, face masks, and eye protection on virus transmission in health-care and non-health-care (eg, community) settings.
UPDATED
5/31/20
Co-infections in people wi
Lansbury L, Lim WS, Baskaran V, et al. | J Infect
Aim: To evaluate the burden of co-infections in patients with COVID-19.
UPDATED
5/28/20
Diabetes care during COVID
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on risk stratification approaches to identify risk level in diabetes patients and clinical pathways to support diabetes management and service delivery.
UPDATED
5/28/20
Domestic and family violen
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the risk of domestic and family violence during the COVID-19 pandemic.
UPDATED
5/28/20
Fibrinolysis and PCI for S
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on fibrinolysis versus primary percutaneous coronary intervention in the treatment of ST-Elevation Myocardial Infarction (STEMI).
UPDATED
5/28/20
Inpatient management of CO
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the available guidelines on inpatient management of COVID-19.
UPDATED
5/28/20
Intubation in the emergenc
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on safe practice of intubation in the emergency department during the COVID-19 pandemic.
UPDATED
5/28/20
Neonates and COVID-19
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the risk of newborn babies developing COVID-19.
UPDATED
5/28/20
NIPPV and requirements
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on how the increasing use of NIPPV to manage suspected or confirmed COVID-19 patients led to any additional guidance regarding the physical requirements and engineering services.
UPDATED
5/28/20
Pulmonary rehabilitation a
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the guidance for the provision of pulmonary rehabilitation for people recovering from COVID-19.
UPDATED
5/28/20
Rehabilitation needs of po
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the rehabilitation needs of post-acute COVID-19 patients and the appropriate timing of rehabilitation interventions.
UPDATED
5/28/20
Scope, quality, and inclus
Dagens A, Sigfrid L, Cai E, et al. | BMJ
Aim: To appraise the availability, quality, and inclusivity of clinical guidelines produced in the early stage of the coronavirus disease 2019 (covid-19) pandemic.
UPDATED
5/28/20
Spirometry and transmissio
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on spirometry and whether it's an aerosol generating procedure, and the risk this procedure carries during the COVID-19 pandemic.
UPDATED
5/28/20
Temporary shared accommoda
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the available guidelines on temporary shared accomodations, particularly for people experiencing homelessness.
UPDATED
5/28/20
Thermal imaging for detect
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the effectiveness of mass thermal imaging in identifying people with COVID-19.
UPDATED
5/28/20
Validated tools to diagnos
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on which tools are validated to diagnose respiratory illness via telehealth.
UPDATED
5/28/20
Ventilation use for COVID-
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the proportion of COVID-19 cases in intensive care units that require ventilation.
UPDATED
5/27/20
Predictive Symptoms and Co
Jain V, Yuan JM  | Int J Public Health
Aim: To identify specific symptoms and comorbidities predicting severe COVID-19 and intensive care unit (ICU) admission.
UPDATED
5/27/20
Treatments administered to
Fajgenbaum DC, Khor JS, Gorzewski A, et al. | Infect Dis Ther
Aim: To systematically evaluate the treatments adminstered to COVID-19 patients.
UPDATED
CANDIDATE THERAPEUTICS
5/19/20
Immunosuppression and COVI
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on the risk and management of people with immunosuppression and COVID-19.
UPDATED
5/19/20
Telehealth and COVID-19
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence or published standards on telehealth implementation during the COVID-19 pandemic.
UPDATED
5/18/20
LIVING SYSTEMATIC REVIEW:
Mackey K, King VJ, Gurley S, et al. | VA Evidence Synthesis Program
Aim: To synthesize evidence on the role of ACE inhibitor and ARB use on patient outcomes in COVID-19 as well as evidence on the benefits and harms of initiating these medications to treat patients with COVID-19.
UPDATED
WHO COLLABORATIVE
VA ESP
5/14/20
Safe management of bodies
Yaacoub S, Schunemann H, Khabasa J, et al. | BMJ Global Health
Aim: To systematically review the literature to scope and assess the effects of specific strategies for the management of the bodies.
UPDATED
WHO COLLABORATIVE
5/6/20
COVID-19 in children with
LeBlanc A | medRxiv
UPDATED
4/21/20
Testing before surgery
 | NSW Health COVID-19 Critical Intelligence Unit
Aim: To review the evidence on preoperative testing of COVID-19 for patients undergoing surgery.
UPDATED
4/18/20
A living systematic review
Della Gatta A, Rizzo R, Pilu G, et al. | Am J Obstet Gynecol
Aim: To conduct a systematic review of the clinical outcomes reported for pregnant patients with coronavirus disease 2019.
UPDATED